With great pleasure I am writing few words for the new Journal - Medical Science, where I am serving as Chief Editor. Remarkable advancements have been made in the field of Medical, Dental, Nursing and Allied health sciences during the past 10 years. It influenced our life expectancy, better health management; treatment in an improved way, even its impact can be seen in health policy of governments of different countries. The major objective of the journal - Medical Science is to encourage physicians through the Internet, especially we focus in the developing countries doctors, scientists, dentists, nurses and allied health science workers who are the witness of a spectrum of disease and acquire a wealth of knowledge for the benefit of the health science community by means of scientific online publication. The rate of advancements in Medical, Dental, nursing and allied health sciences field is so enormous that it takes time for them to know properly about its application. Medical Science journal has launched to bring out all the research activities from Medical, Dental, Nursing and Allied health sciences under a common platform, so that advancements from all these fields can be published in one journal and freely accessible for everyone. Knowledge without distribution has no value. Advancements of science and technology in the past few years gave birth of the World Wide Web which is helping people for sharing the information’s, advancements in different fields for the wellbeing of human civilization. Keeping this in mind we started our journal as online to provide a free of cost access from any part of the world. Journal editorial team will try their best to take several initiatives that will improve the quality of reporting and we have given prime importance to the transparency of research in general, and randomized trials in particular, by emphasizing the importance of protocols. We consider submissions of randomized trials only if registered and accompanied by a protocol, which is sent with the manuscript to peer reviewers. We aspire to make this journal one of the best journals that will follow standard criteria of scientific article writing along with sound technical proficiency. Due to excessive workload and time constraints, it is really difficult for physicians who may lack the motivation for writing a research article. Keeping this in mind the Medical Science also offers a range of several other services which include - peer review, proof reading, setting up of the bibliography, and English language improvement. The main motto is to assist, so that they can share their clinical knowledge by the platform of Medical Science Journal. Our editorial team came up with a determination to make it as one of the best journals in Asia with everybody’s effort and whole hearted support. We promise you to come to your expectation and also make it an international indexed journal. However, for all this we need your contribution in the future issues. This journal and its services are not affiliated to any pharmaceutical or other company. It is a philanthropic effort by Confederation of Medical Research Associations, India. At this auspicious moment it would be extremely remiss on my part if I don’t acknowledge the contribution and express my gratitude to the many people whose blessings, active cooperation and help make our journal to come up with a novel vision. Lastly I must thank my parents, sister, wife, my teachers and colleagues who encourage me to start Medical Science journal.

Background: Diverse factors play a crucial role on the Career Preferences among medical students. Hospital-based clinical specialties are always preferred. Nepal had very scanty data on this topic. So this study was designed to examine the influence of gender and nationality, some other dominant factors including drawbacks in future career preferences. Methods: A questionnaire-based study was carried out in the Basic and clinical Sciences Campus of Manipal College of Medical Sciences, Pokhara, Nepal. Students from Nepal, India and Sri Lanka participated in the study. The questionnaire included awareness and liking of different subjects for post-graduation, decision age for MBBS and various other factors. Descriptive statistics and testing of hypothesis were used for the analysis. The Chi-square test was performed. Data was analyzed using Statistical Package for the Social Sciences (SPSS) for Windows Version 16.0. Results: Data was collected from 269 students and among them were 110 Nepalese (40.9%), 85 Indian (31.6%) and 74 Sri Lankan (27.5%). Indian students had relatively more awareness about their future career. Females were more aware about future career and happy with routine work, diversity in work, physical and team work. Communication skills, long relation with patients, simple complaints and stressful work attract males. Surgery, OBG, Pediatrics, Neurosurgery, Cardiology were the most desirable specialty among both genders. Conclusion: The findings of this study were imperative and provide ample career guidance for future doctors to fill the gap in different specialties. Constructive steps like encouragement, counseling can be helpful in this context.

Background: In Nepal several research studies are reported using percentages or cross tabulation method, but the relevance of logistic regression methodology in research is lag behind among the researchers. Objectives: The main objective of this study was to find the role of logistic regression analysis in the pattern of antidepressants in a tertiary care center in hospitalized patients of Western Nepal. Methods: A hospital based study was done between 1st October 2009 and 31st March 2010 at Psychiatry Ward of Manipal Teaching Hospital, Nepal. Z test, Chi square test and Binary logistic regression were used for the analysis. We calculated odds ratios (OR) and their 95% confidence intervals (95% CI) P-value < 0.05 was considered to be statistically significant. Different codes were used, the target was coded as 1 and the reference group as 0. Results: The results of the study were interesting as far as the gender is concerned, male and female patients were 44.7% and 55.3% respectively, 95% CI [28.9, 60.5 and 39.5, 71.1]. Depression was more common in housewives 42.1%. Fluoxetine was the commonest antidepressants to be prescribed 42.1%. Psychiatrists has a tendency of prescribing essential drugs if monthly income <10000, 1.063 times as compared to monthly income >10000, 2.63 times more in Hindus and 1.197 times more in Brahmins than any other ethnic groups. 9.179 times more tendency of prescribing antidepressants by trade names in case of unemployed patients as compared to employed patients in Nepal. Conclusion: Binary Logistic regression plays an important role to understand the drug utilization pattern of mood elevators in Western Nepal.

Background: Computer is a part of our daily life. In Medical Science it has become an essential product in every hospital. Starting from open heart surgeries to X rays to various clinical tests all are carried out by the help of computer. They communicate with each other by email, live chatting and they also use to take full advantage of technology. They also use the computer and internet nearly as much for social communication as they do for their educational purposes. Methods: This cross-sectional study was conducted from January to August 2010 at NMC, Birgunj, Nepal. The subjects of this survey were Undergraduate medical students. Results: Most of the students were in the age group of 21- 23yrs and 19 – 20 yrs. Males were more in number (62%) compared with females. Among Ist yr students computer as a Source of information got priority but in IInd year students Source of information Preparing notes and reading Research articles were more important. Amusement and Preparing notes and reading Research articles were important factor for IIIrd & IVth Year students. Conclusion: The use of the laptop and personal computers along with internet connectivity is increasing. This is becoming a part of medical education in different parts of the globe. In this study on medical students we observed an association between the year of study and the purpose of computer and internet use. Computer assisted teaching learning activities should be encouraged for the improvement of medical science for the new generations.

Background: Computer is a part of our daily life. In Medical Science it has become an essential product in every hospital. Starting from open heart surgeries to X rays to various clinical tests all are carried out by the help of computer. They communicate with each other by email, live chatting and they also use to take full advantage of technology. They also use the computer and internet nearly as much for social communication as they do for their educational purposes. Methods: This cross-sectional study was conducted from January to August 2010 at NMC, Birgunj, Nepal. The subjects of this survey were Undergraduate medical students. Results: Most of the students were in the age group of 21- 23yrs and 19 – 20 yrs. Males were more in number (62%) compared with females. Among Ist yr students computer as a Source of information got priority but in IInd year students Source of information Preparing notes and reading Research articles were more important. Amusement and Preparing notes and reading Research articles were important factor for IIIrd & IVth Year students. Conclusion: The use of the laptop and personal computers along with internet connectivity is increasing. This is becoming a part of medical education in different parts of the globe. In this study on medical students we observed an association between the year of study and the purpose of computer and internet use. Computer assisted teaching learning activities should be encouraged for the improvement of medical science for the new generations.

Communication with the patient is an art. A medical professional can earn a lot of degrees but communicating with the patient always remains a problem for some of them. Communication plays a key role to make him/her successful in Life .Communication Skill is an important part of the pharmacology teaching and learning session followed at Manipal College of Medical Sciences. Most of the textbooks that are commonly followed in Nepal merely tell about communication skills. In Communication Skills it is taught that how to speak/communicate with the patient right from the beginning when a student is admitted to the medical school. This activity makes the student confident. Some of the important concepts of Communication Skill are mentioned in this paper.